Résumé:
The creation of C
-
C bound link Direct current is for a long time one of the research axles
favour chemistry. The heterocycl
of the tétrahydroisoquinolines
is among classical divisions
of organic chemistry belong to alkaloids which develop most faster they occup
p
a
predominating place in the industry of the pharmaceutical products and quite other areas of
chemistry.
All that was translated by the synthesis o
f a big number of new
heterocyclic
compounds, so
the introduction of new functional groupings in structures of tétrahydroisoquinolines for
instance, allowed the preparation of a broad variety of these compounds.
Our work is dedicated to the converging synt
hesis of various THIQs chirales not racémiques
in a pyrroloisoquinoline and a tétrahydroprotoberbérine. These two diverting are no oxygen
analogues of natural products as (
-
)
-
crispine A and (
-
)
-
xylopinine.
The chiralité is brought with the aid of the r
eaction of Zincke by enlistment of l ’
α
-
PEA on
salt of isoquinolinium. An analytical study allows to define surgical conditions at best and
particularly to put in an obvious place a phenomenon of catalysis redox between the radical
cation and ions potas
sium cyanide.
Électrochemical Syntheses of the oxadiazoles from
semicarbazone after an analytical study is accomplished with the aid of a electrode of vitreous
carbon in methyl alcohol in the presence of LiClO4 (20 g/L) as electrolyte support.
