Abstract:
Our experimentation permitted on one hand the establishment of the structures of eight
lactones in the native state whose two original, four structures acctylcted and two
polymethoxyleted flavones from two Algerian species (Ceniaurea musimomum
Centaurea granula L) of which one endemic (Ceniaurea musimomum). On the other hand
the working up of the cytotoxic activity and antiparasitic of the chloroformic extracts of the
two former species and the two other endemic species (( enlaurea furfuracea and ('entaurca
maroccana). These tests have been shown interesting activities of Ceniaurea musimomum and
Ceniaurea furfuracea and less important activities for ( enlaurea granola L and Ceniaurea
maroccana. Concerning isolated principles, only one guaianolidc was tested in this work.
The determination of structures has been realised by combining the results of
spectroscopic methods and particularly the most preferment sequences of N.M.R multi¬
impulsion mono and bidimensionnels. The crystalline aspect of some products has permitted
to have recourse to the technique of diffraction of RX for two of them.
