Étude phytochimique et évaluation du potentiel antioxydant des espèces Anagallis monelli ssp. linifolia L. et Arenaria cerastioides Po.

Abstract

The present study focused on the phytochemical investigation and the evaluation of the antioxidant activity of two plants: Anagallis monelli ssp. linifolia (L.) (Primulaceae) and Arenaria cerastioides (poir.) (Caryophyllaceae). A total of 26 compounds were isolated, including 13 new saponins, using various chromatographic methods such as TLC, VLC, CC, FCC, PLC, and HPLC. The structures of the isolated compounds were elucidated using 1D (1H and 13C) and 2D (COSY, HSQC, HMBC, TOCSY, and ROESY) NMR techniques, high-resolution mass spectrometry (HR-ESI-MS) and by comparison with literature data, along with measurement of optical rotation [α]D. The antioxidant activity was evaluated using three methods: DPPH, ABTS, and CUPRAC. The results showed that the acetate extract of the Arenaria cerastioides species (Far/A) exhibited excellent antioxidant activity compared to standards BHT and BHA, followed by the acetate extract of Anagallis monelli ssp. linifolia species (Fan/A).