Browsing Magistère (Biochimie) by Author "Bensegueni, Abdellatif"

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Conception in silico de nouveaux inhibiteurs de la topoisomérase I de cellules cancéreuses.

Teniou, Soumia; Bensegueni, Abdellatif (Université Frères Mentouri - Constantine 1, 2012-01-01)

Human DNA Topoisomérase I (topo I) is the tar get of several drugs commonly used in cancer chemotherapy. These drugs induce topo-DNA co mplexes that eventually trigger cell death. Several ...
Contribution à l’amélioration de l’activité biologique des inhibiteurs de la dipeptidyl-peptidase 4 dans le diabète de type 2 par simulation informatique.

Mokrani, El-Hassen; Bensegueni, Abdellatif (Université Frères Mentouri - Constantine 1, 2012-01-25)

Type 2 diabetes mellitus (T2DM) is a severe and increasingly prevalent disease that is considered as a major global public health. It engenders about four millions death in the world.In our research, we focus on type 2 ...

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