Comparaison des effets sédatifs et analgésiques de deux molécules morphiniques en association avec de l’acépromazine

Abstract

"In canine practice, many acts require tranquilization for the animal. So we need to find protocols that generate deep sedation, good analgesia and minimal side effects. This study, conducted in double-blind, on 10 dogs, compared sedative, analgesic, cardiovascular, respiratory and changes in certain biochemical parameters (blood glucose, hematocrit and total protein) of morphine and fentanyl both associated with the acepromazine in sedation of dogs. It suggests that acepromazine /fentanyl association provided sedation similar to acepromazine / morphine association, but not as longer duration of action intensity as acepromazine / morphine association. Under the sedative efficacy and greater safety of the association, it appears desirable to promote clinical multimodal approach more than monotherapy approach under sedation of the dog or cat."